INTRODUCTION Of Migraine & Epilepsy

1. Neurological chronic disorders with manifestations (CDEM) are characterized by recurrent attacks of nervous system dysfunction with a return to baseline between attacks. Among the CDEM treated by neurologists, headaches (including migraine) and epilepsy are the most common, each compressing nearly 20% of out patient neurological visits.

2. Both migraine and epilepsy represent dist inch families of neurological disorders with typical constellations of symptoms. Migraine is characterized by recurrent attacks of pain and associated symptoms.

3. Epilepsy is characterized by recurrent attacks of positive neurological symptoms, often progressing to altered of lost consciousness, and at times
convulsive features.

4. The physician while treating these disorders face many challenges. The sensory, motor and cognitive characteristics of migraine and epilepsy often overlap. Both disorders presents with headache.

5. Furthermore, as migraine and epilepsy are highly co morbid, many individuals have both disorders, further complicating accurate diagnosis.Additionally, the therapeutic options for the disorders overlap.

6. Migraine may be co morbid with several other neuralgic and psychiatric conditions, including mood disorders (eg, depression, anxiety and panic disorders), epilepsy, stork and essential tremor. Co morbidity presents physicians with opportunities and and challenges for both and treatment.

"Both Migraine and epilepsy are heterogeneous families of chronic disorders with highly variable clinical features,natural histories, and patterns of treatment response. Both are characterized by episodes of
neurology's dysfunction, sometimes accompanied by
headache as well as gastrointestinal,
autonomic and psychological
features."

all diseases must be considered, and therapeutic strategics may need to be modified to avoid potential drug interactions. Commodities also may provide clues to the parapsychology's and any shared mechanisms of two disorders.

Longitudinal studies have demonstrated a bi-directional influence between migraine and major depression, but not between migraine and other severe headache. Migraine is strongly and consistently associated with panic disorder. The risk of migraine in epilepsy is increased particularly in individuals with head trauma, partial seizures, and a positive family history of migraine. The influence is bidirectional.

There is also growing evidence of an association between migraine and stroke, particularly among women of child-bearing age and individuals who experience migraine with aura. Lastly, a bidirectional association between migraine and essential tremor also exists. These findings suggests that migraine, major depression, epilepsy,and essential tremor shares one or common etiologies.